The base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. If the role is non-exempt, overtime pay will be provided consistent with applicable laws. In addition to the salary range listed above, total compensation also includes generous equity, performance-related bonus(es) for eligible employees, and the following benefits.

• Medical, dental, and vision insurance for you and your family, with employer contributions to Health Savings Accounts

• Pre-tax accounts for Health FSA, Dependent Care FSA, and commuter expenses (parking and transit)

• 401(k) retirement plan with employer match

• Paid parental leave (up to 24 weeks for birth parents and 20 weeks for non-birthing parents), plus paid medical and caregiver leave (up to 8 weeks)

• Paid time off: flexible PTO for exempt employees and up to 15 days annually for non-exempt employees

• 13+ paid company holidays, and multiple paid coordinated company office closures throughout the year for focus and recharge, plus paid sick or safe time (1 hour per 30 hours worked, or more, as required by applicable state or local law)

• Mental health and wellness support

• Employer-paid basic life and disability coverage

• Annual learning and development stipend to fuel your professional growth

• Daily meals in our offices, and meal delivery credits as eligible

• Relocation support for eligible employees

• Additional taxable fringe benefits, such as charitable donation matching and wellness stipends, may also be provided.

More details about our benefits are available to candidates during the hiring process.

This role is at-will and OpenAI reserves the right to modify base pay and other compensation components at any time based on individual performance, team or company results, or market conditions.

About the team

OpenAI’s Forward Deployed Engineering team partners with global pharma and biotech, CROs, and research institutions to deploy existing expertise across the R&D value chain to help customers design and ship production-grade AI systems. We operate at the intersection of customer delivery and core platform development, converting early deployments into repeatable system standards and evaluation practices that scale across regulated environments.

About the role

We are hiring a Forward Deployed Engineer (FDE) to push the frontier on what is possible today across drug discovery (e.g., target identification, molecular design, pre-clinical) and development (e.g., trial design, trial ops, biostats) by leading end-to-end deployments of our models inside life sciences organizations and research institutions. You will work with customers who are deep experts in their scientific or operational domains, translating real-world data, infrastructure, and constraints into production systems.

You will measure success through production adoption, measurable workflow impact, and eval-driven feedback loops, including evaluation benchmarks and acceptance criteria, that inform product and model roadmaps. You’ll work closely with our Product, Research, Partnerships, GRC, Security, and GTM to deliver in regulated contexts, including inspection readiness with audit trails and traceable evidence.

This role is based in NYC. We use a hybrid work model of 3 days in the office per week. We offer relocation assistance. Travel up to 50% is required.

In this role you will

• Design and ship production systems around models, owning integrations, data provenance, reliability, and on-call readiness across research, clinical, and operational workflows.

• Lead discovery and scoping from pre-sales through post-sales, translating ambiguous workflow needs into hypothesis-driven problem framing, system requirements, and an execution plan with measurable endpoints.

• Define and enforce launch criteria for regulated contexts, including validation evidence, audit readiness, outcome metrics, and drive delivery until we demonstrate sustained production impact.

• Build in sensitive scientific data environments where auditability, validation, and access controls shape architecture, operating procedures, and failure handling.

• Run evaluation loops that measure model and system quality against workflow-specific scientific benchmarks and use results to drive model and product changes.

• Distill deployment learnings into hardened primitives, reference architectures, validation templates, and benchmark harnesses that scale across regulated life sciences environments.

You might thrive in this role if you

• Bring 5+ years of software/ML engineering or technical deployment experience with customer-facing ownership in biotech, pharma, clinical research, or scientific software; PhD, MS, or equivalent applied experience in a life sciences relevant field encouraged.

• Have owned customer GenAI deployments end-to-end from scoping through production adoption, and improved them through evaluation design, error analysis, and iterative evidence generation that tightens acceptance criteria over time.

• Have delivered AI systems in trial design, regulatory writing, or scientific operations where validation strategy, auditability, compliance constraints, and reviewer expectations shaped system design and rollout.

• Communicate clearly across scientific, clinical, model research, technical, and executive audiences, translating technical tradeoffs into decision quality, risk posture, and measurable outcomes with credibility.

• Apply systems thinking with high execution standards, consistently turning failures, escalations, and audit findings into improved operating standards, validation artifacts, and repeatable deployment playbooks.

About OpenAI

OpenAI is an AI research and deployment company dedicated to ensuring that general-purpose artificial intelligence benefits all of humanity. We push the boundaries of the capabilities of AI systems and seek to safely deploy them to the world through our products. AI is an extremely powerful tool that must be created with safety and human needs at its core, and to achieve our mission, we must encompass and value the many different perspectives, voices, and experiences that form the full spectrum of humanity.

We are an equal opportunity employer, and we do not discriminate on the basis of race, religion, color, national origin, sex, sexual orientation, age, veteran status, disability, genetic information, or other applicable legally protected characteristic.

For additional information, please see OpenAI’s Affirmative Action and Equal Employment Opportunity Policy Statement.

Background checks for applicants will be administered in accordance with applicable law, and qualified applicants with arrest or conviction records will be considered for employment consistent with those laws, including the San Francisco Fair Chance Ordinance, the Los Angeles County Fair Chance Ordinance for Employers, and the California Fair Chance Act, for US-based candidates. For unincorporated Los Angeles County workers: we reasonably believe that criminal history may have a direct, adverse and negative relationship with the following job duties, potentially resulting in the withdrawal of a conditional offer of employment: protect computer hardware entrusted to you from theft, loss or damage; return all computer hardware in your possession (including the data contained therein) upon termination of employment or end of assignment; and maintain the confidentiality of proprietary, confidential, and non-public information. In addition, job duties require access to secure and protected information technology systems and related data security obligations.

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We are committed to providing reasonable accommodations to applicants with disabilities, and requests can be made via this link.

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At OpenAI, we believe artificial intelligence has the potential to help people solve immense global challenges, and we want the upside of AI to be widely shared. Join us in shaping the future of technology.

Compensation Range: $220K - $280K